1. Identification and expression profiling of blood brain barrier membrane proteins. Agarwal, N, Lippmann, E.S., Shusta, E.V., Journal of Neurochemistry 2010; 112; 625-635 PDF

  2. Expression of novel molecules, MICAL2-PV (MICAL 2 prostate cancer variants), increases with high Gleason score and prostrate progress. Ashida, S., Furihata, M., Katagiri, T., Tamura, K., Anazawa, Y., Yoshioka, H., Miki, T., Shuin, T., Nakamura, Y., Nakagowa, H. Clin. Cancer Res. 12 2767-2773

  3. Molecular features of the transition from prostastic intrapethelial neoplasia (PIN) to prostrate cancer: genome-wide gene expression profiles of prostrate cancer and PINs. Ashida, S., Nakagowa, H., Katagiri, T., Furihata, M.,Iiizumi, M., Anazawa, Y., Tsunodo T., Takata, R., Kashara, K., Miki, T., Fujioka, T., Shuin, T., Nakamura, Y. Cancer Res. 64, 5963-5972 PDF

  4. Microbeam MOMenNT: non contact laser microdissection of membrance –mounted native tissue. Bohm, M., Wieland, I. Schutze, K., Rubben, H. Am. J. Pathol. 151, 63-67 PDF

  5. Use of immune-LCM to identify the in situ expression profile of cellular constituents of the tumor microenvironment. Buckanovich, R.J., Sasaroli, D., O’Brien-Jenkins, A., Botbyl,j., Conejo-Garcia, J.R., Benencia, F., Liotta, L. A., Gimotty, P.A., Coukos, G. Cancer Biol Ther. 5, 635-642 PDF

  6. Tumor vascular proteins as biomarkers in Ovarian Cancer. . Buckanovich, R.J., Sasaroli, D., O’Brien-Jenkins, A., Botbyl,j., Hammond R., Katsaros, D., Sandaltzopoulos, R., Conejo-Garcia, J.R., Liotta, L. A., Gimotty, P.A., Coukos, G. J. Clin. Oncol. 25, 852-861 PDF

  7. Proteomic analysis of human breast cancer tissue with laser-capture microdissection and reverse phase protein microarrays. Cowherd, S.M., Espina, V. A., Petricion, E.F., III, Liotta, L.A., Clin. Breast Cancer 5, 385-392

  8. Gene expression analysis of the microvascular compartment in multiple sclerosis using laser microdissected blood vessels. Cunnea, P., McMahon, J., O’Connell, E., Mashayekhi, K., Fitzgerald, U., McQuaid, S. Acta Neuropathol 2010; 119; 601-615 PDF

  9. Molecular profiling of laser –microdisected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer. Dahl, E., Kristiansen, G., Gottlab, K., Klaman, I., Ebner, E., Hinzmann, B., Hermann, K., Pilarsky, C., Durst, M., Klinhammer-Schalke, M., Blaszyk, h., Kneuchel, R., Hartmann, A., Rosenthal, A., Wild, P.J. Clin Cancer Res. 12, 3950-3960. PDF

  10. Quantitative RT-PCR gene expression analysis of laser microdissected tissue samples. Erickson, S.H., Albert, S.P., Gillespie, W.J., Canales-Rodriguez, J., Line-han, M.W., Pinto, A.P., Chuaqui, F.R., Emmert-Buck, R.M., Nat Protoc. 2009, 4, 902-922

  11. Use of proteomic analysis to monitor responses to biological therapies. Espina, V., Dettloff, K.A., Cowherd, S., Petricion, E.F., III, Liotta, L.A. Expert. Opin. Biol. Ther. 4, 83-93

  12. Laser-capture microdissection technology. Espina, V., Heiby, M., Pieroban, M., Liotta, L.A. Expert. Rev. Mol. Diagn. 7, 647-657

  13. Laser-capture microdissection. Espina, V., Wulfkuhle, J.D., Calvert, V.S., VanMeter, A., Zhou, W., Coukos, G., Geho, D.H., Petricoin, E.F., III, Liotta, L.A. Nat. Protoc. 1, 586-603

  14. Wnt/beta-catenin is essential homeostasis and maintenance of intenstinal stem cells. Fevr, T., Robine, S., Louvard, D., Huelsken, J. Mol. Cell Biol. 27, 7551-7559. PDF

  15. Voltage-gated sodium channels in taste bud cells. Gao, N., Lu, M., Echeverri, F., Laita, B., Kalabat, D., Williams, E.M., Hevezi, P., Zlotnik, A., Moyer, D.B. BMC Neurosci. 2010; 10-20

  16. The influence of immunochemistry on mRNA recovery from microdissected frozen and formalin-fixed, paraffin-embedded sections. Gjerdrum, L.M., Abrahamsen, H.N., Villegas, B., Sorenson, B.s., Schmidt., Hamilton-Dutoit, S.J. Diagno. Mol. Pathol. 13, 224-233

  17. Laser-assisted microdissection of membrane-mounted sections following immunochemistry and in situ hybridization. Gjerdrum, L.M. Hamilton-Dutoit, S. Methods Mol. Biol. 293, 139-149.

  18. Laser-assisted microdissection of membrane-mounted tissue sections. Gjerdrum, L.M. Hamilton-Dutoit, S. Methods Mol. Biol. 29
    3, 127-138

  19. Laser-assisted microdissection of membrane-mounted paraffin sections for Polymerase chain reaction analysis: Identification of cell populations using immunohistochemistry and in situ hybridization. Jerdrum, L.M., Lielpetere, I., Rasmussen, L.M., Bendix, K., Hamilton-Dutoit, S. J. Mol. Diagn. 3, 105-110

  20. AhR-medicated gene expression in the developing mouse telencephalon. Gohikle, M.J., Stockton, S.P., Sieber, S., Foley, J., Portier, J., Reproductive Toxicology, 28, 312-328. PDF

  21. Contaminating cells alter gene signatures in whole organ versus laser capture microdissected tumors: a comparison of experimental breast cancers and their lymph mode metasteses. Harrel, C.J., Dye, W.W., Harvell, E.M.D., Sartorius, A.C., Horwitz, B.K., Clin. Exp. Metastasis. 2008; 25(1) 81-89

  22. Protein clusters associated with carcinogenesis, histological differentiations and nodal metastasis in esophageal cancer. Hatakeyama, H., Kondo, T., Fujii, K., Nakanishi, Y., Kato, H., Fukuda, S., Hirohashi, S. Proteomics. 6, 6300-6316. PDF

  23. MicroRNA expression profiling of specific cells in complex archival tissue stained by immunohistochemistry. Schuster, C., Budczies, J., Kirchner, T., Hlubek, F., Lab. Invest. 2011 Jan 91(1) 157-165. PDF

  24. Genome-wide analysis of gene expression in primate taste buds reveals links to diverse processes. Hevezi, P., Moyer, B.D., Lu, M., Gao, N., White, E., PLoS One (2009) 4: e6395 PDF

  25. Heterogeneous expression of WnT/β-Catenin target genes within colorectal cancer. Hlubek, F., Bradletz, T., Budczies, J., Pfeiffer, S., Jung, A., Kirchner, T., Int. J. Cancer: 121, 1941-1948 PDF

  26. Connexin 45 expression in the human obstructed detrusor muscle. John H., Walch, M., Lehmann, T., Maake, C. World J. Urol. 2009; 27; 411-418. PDF

  27. Laser capture mirodissection of gonada from juvenile zebrafish; Jorgensen A., Nielsen J.E., Morthorst, J.E., Bjerregaard, P., Leffers, H. Repro. Biol & Endo. 2009, 7:97 doi 10.1186/1477 PDF

  28. The Human LAPTM4b transcript is upregulated in various types of solid tumours and seems to play a dual functional role during tumour progeression. Kasper, G., Vogel, A., Klaman, I., Grone, J., Petersen, I., Weber, B., Castanos-Velez, E., Staub, E., Mennerich, D. Cancer Lett. 224, 93-103

  29. Expression levels of the putative zinc transporter LIV-1 are associated with a better outcome of breast cancer patients. Kasper, G., Weiser, A.A., Rump, A., Sparbier, K., Dahl, E., Hartmann, A., Wild, P., Schwidetzky, U., Castanos-Velez, E., Lehmann, K. Int. J. Cancer 117, 961-973 PDF

  30. Applications of highly sensitive fluorescent dyes (CyDye DIGE Fluor saturation dyes) to laser micr-dissection and two-diemsional difference gel electrophoresis (2D-DIGE) for cancer proteomics. Kondo, T., Hirohashi, S., Nat. Protoc. 1, 2940-2956. PDF

  31. Optimization of laser capture microdissection and RNA amplification for gene expression profiling of prostrate cancer. Kube, D.M., Savci-Heijnk, C.D., Lamblin, A.F., Kosari, F., Vasmatzis, G., Cheville, J.C., Connelly, D.P., Klee, G.G. BMC. Mol. Biol. 8, 25 PDF

  32. Elevated alph-methylacyl- CoA racemase enzymatic activity in prostate cancer. Kumar-Sinha, C., Shah, R.B., Laxman, B., Tomlins, S.A., Harwood, J., Schmitz, W., Conzelmann, E., Sanda, M.G., Wei, J.T., Rubin, M.A., Chinnaiyan, A.M. Am. J. Pathol. 164, 787-793

  33. A novel approach for reliable microarray analysis of microdissected tumor cells from formalin-fixed and paraffin-embedded colorectal cancer resection specimens. Lassman, S., Kreutz, C., Schoepflin, A., Hopt, U., Timmer, J., Werner, M. J.Mol.Med. 2009; 87; 211-224 PDF

  34. Two-diemensional transcriptome profiling: Identification of messanger RNA isoform signatures in prostate cancer from archived paraffin-embedded cancer specimens. Li, H-R., Wang-Rodriguez, J., Murlidharan Nair, T., Yeakley, J.M., Kwon, Y-S., Bibkova, M., Zheng, C., Zhou, L., Zhang, K., Downs, T., Fu, X-D., Fan, J.B., Cancer Res. 2006; (4) 15; 66 (8) 4079-4088 PDF

  35. Methods comparison for high-resolution transcriptional analysis of archival material of Affymetrix Plus 2.0 and Exon 1.0 microarrays. Linton, K., Hey, Y., Dibben, s., Miller, C.J., Freemont, A.J., Radford, J.A., Pepper S.D. BioTechniques 2009; 47(1); 587-596. PDF

  36. Abnormalities of the APC/β-catenin pathway in endometrical cancer. Moreno-Bueno, G., Hardison, D., Sanchez, C., Sarrio, D., Cassia, R., Garcia-RG., Prat, J., Guo, M., Herman, J.G., Matias-Guiu, X., Esteller, M., Palacios, J. Onogene 2002, 21, 7981-7990.

  37. Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma. Obama, K., Ura, K., Li, M., Katagiri, T., Tsunoda., Nomura., Satoh, S., Nakamura, Y., Furukawa, Y. Hepatology, 2005, 41, 1339-1348.

  38. Correlation of EGFR mutations and increases in EGFR and HER2 copy number to getitnib response in a retrospective analysis of lung cancer patients. Pugh, T.J., Bebb, G., Barclay, L., Sutcliffe, M., Fee, J., Salski, C., O’Connor, R., Ho, C., Murray, N., Melosky, B., English, J., Vielkind, J., Horsmann, D., Laskin, J.J., Marra, M.A. Cancer, 2007, 7, 128. PDF

  39. Novel Biomarkers for Prostrate cancer noncoding thranscripts. Romaniuk, T.L., Ueda, T., Le, N., Haile, S., Yong, T.M.K., Thomson, T., Vessella, R.L., Sadar, M.D., Am. J. Pathol. 2009; 175; 2264-2276.

  40. Silencing of the p18INK-4c gene by promoter hypermethylation in Reed-Sternberg cells in Hodgkin lymphomas. Sanchez-Aguilera, A., Delgado, J., Camacho, F.I., Sanchez-Beato, M., Sanchez, L., Montalban, C., Fresno, M.f., Martin, C., Piris, M.A., Garcia, J.F., Blood, 2004, 103, 2351-2357.

  41. A role for motorneuron subtype-selective ER stress in disease manifestations of FALS mice. Saxena, S., Cabuy, E., Caroni, P.,. Nat Neurosci. May 2009; 12(5) 627-636.

  42. Increased expression of Met protein is associated with up-regulation of hypoxia inducible factor-1 (HIF-1) in tumour cells in papillary carcinoma of the thyroid. Scarpino, S., Cancellario, D.F., Di, N.A., Pasquini, A. Marzullo, A., Ruco, L.P. J. Pathol., 2004, 2002, 352-358

  43. Paillary carcinoma of the thyroid: low expression of NCAM (CD56) is associated with downregulation of VEGf-D production by tumour cells. . Scarpino, S., Cancellario, D.F., Di, N.A., Pasquini, A. Marzullo, A., Ruco, L.P. J. Pathol., 2007, 212, 411-419

  44. Papillary carcinoma of the thyroid;methylation is not involved in the regulation of MET. Scarpino, S., Di, N.A., Rapazzotti-Onelii, M., Pilozzi, E., Ruco, L. Br. J. Cancer 2004, 91, 703-706

  45. Scarpino, S., Di, N.A., Stoppacciaro, A. Antonelli, M., Pilozzi, E., Chiarle, R., Palestro G., Marino, M., Facciolo, F., Rendina, E.A., Webster, K.E., Kinkel, S.A., Scott, H.S., Ruco, L. Clin. Exp. Immunol. 2007, 149, 504-512

  46. Heptatocyte growth factor (HGF) downregulates thrombospondin 1 (TSP-1) expression in thyroid papillary Carcinoma cells. Scarpino, S., Di, N.A., Taraboletti, G., Carcrini, A., Ruco,L. J. Pathol. 2005, 205, 50-56

  47. Mutational analysis of the nf2 tumour suppressor gene in three subtypes of primary human malignant mesotheliomas. Schipper, H., Papp, T., Johnen, G., Pemsel, H., Bastrop, R., Muller, K.m., Wiethege, T., Jaworska, M., Krismann, M., Schiffmann, D., Rahman, Q. Int. J. Oncol., 2003, 22, 1009-1017

  48. Optimising staining protocols for Laser Microdissection of specifc cell types for the testis including Carcinoma In situ. Sonne, S.B., Dalgaard, D.M., Nielsen, E.J., Hoei-Hansen, E.C., Rajpert-De Meyts, E., Gjerdum, L.M., Leffers, H. PLoS ONE, May 2009, Vol 4 (5) e 5536

  49. Analysis of gene expression profiles of microdissected cell populations indiacted that testicular carcinoma in situ is an arrested gonocyte. Sonne, S.B., Almstrup, K. Dalgaard, M., Juncker, A.S., Edsgard, D., Ruban, L., Harrison, N.J., Schwager, C., Abdollah, A., Huber, P.E., Brunak, S., Gjerdrum, L.M., Moore, H.D., Andrews, P.W., Shakkebaek, N.E., Rajpert-De Meyts, E., Leffers, H., Cancer Res. 2009 Jun 15; 69(12) 5241-5250.

  50. Developing mRNA based biomarkers from formalin-fixed paraffin-embedded tissue. Tanney, A., Kennedy, R.D., Personalised Medicine, 2010; 7(2) 205-211

  51. Predicting response to methotrexate, vinblastine, doxorubicin and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling. Takata, R., Katagiri, T., Kanehira., Tsunoda, T., Shuin,T., Miki, T., Namiki, M., Kohri, K., Matsushita, Y., Fujioka, T., Nakamura, Y. Clin Cancer Res. 2005, 11, 2625-2636

  52. Molecular features of hormone-refractory prostrate cancer cells by genome-wide gene expression profiles. Tamura, K., Furihata, M., Tsunda, T., Ashida, S., Takata, R., Obara, W., Yoshioka, H., Daigo, Y., Nasu, Y., Kumon, H., Konaka H., Namiki, M., Tozawa, K., Kohri, K., Tanji, N., Yokoyama, M., Shimazui, T., Akaza, H., Mizutani, Y., Miki, T., Fujioka, T., Shuin, T., Nakamura, Y., Nakagawa, H., Cancer Res. 2007; 67, 5117-5125 PDF
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