Our customers include worldwide renowned universities, hospitals, institutes, laboratories and industry. We collaborate closely with customers, researchers and scientists on site, support them, and learn from their experience to develop bespoke workflows to enable them to rapidly meet their goals. Don’t listen to us, instead see what customers have to say about their own experiences and working with MMI.

Molecular Pathology, University of Malta

Shawn Baldacchino
"Our translational cancer research within the Department of Pathology, led by Prof. Godfrey Grech, focuses on particular mechanisms of tumorigenesis for the identification of novel tumour biomarkers and therapeutics. Using a novel approach that utilises a custom-designed technique coupled with Laser Microdissection, we have successfully isolated and measured the RNA expression of specific cell populations from breast cancer tissues to support our investigations of underlying mechanisms.

The MMI CellCut enables us to selectively isolate specific tumour cell populations based on morphology from H&E stained FFPE sections for RNA analysis. Using this methodology, we have isolated distinct malignant clones within heterogeneous tumours as well as microdissected normal breast duct tissue to establish physiological expression levels. Based on gene expression, we classify breast cancer tumours to identify biomarkers towards novel effective therapeutics."

Shawn Baldacchino, PhD
Molecular Pathology Research Team led by Prof Godfrey Grech
Department of Pathology
Faculty of Medicine
University of Malta

Faculty of Veterinary Medicine, Norwegian University of Life Science

Ida Bergva Aas_Customer Testimonial
"At our institute at the Norwegian University of Life Science, many groups are using the MMI CellCut system for various projects.

Our group is mainly interested in investigating the function a lymphoid tissue located in the gills of salmon. Understanding the underlying immune mechanisms is a precondition for the development of successful fish vaccines. 

The MMI CellCut laser microdissection system was applied to selectively isolate the recently discovered interbranchial lymphoid tissue (ILT) from salmon gills. Following RNA extraction we investigated the transcript level of immune-relevant genes in both naïve and challenged fish. This approach provided valuable knowledge concerning the functional role of the ILT.

In addition to the indispensable functionality of the MMI CellCut, we appreciate the helpful and timely service by the MMI team."

Ida Bergva Aas
Faculty of Veterinary Medicine, Norwegian University of Life Science, Oslo, Norway

SIMFO GmbH, Bayreuth, Germany

Monika Pizon Customer Testimonial
"At Simfo, we are interested in analyzing molecular profile of circulating tumor cells (CTCs), because CTCs reflect the real status of tumor genotypes. CTCs exhibit high heterogeneity within a patient and for this reason we analyze individual CTCs for KRAS, BRAF and EGFR mutations.
The MMI CellEctor instrument allows us to precisely select single CTCs from patient samples in order to individually analyze their genomic integrity - an important pre-requisite for our research."

Dr. Monika Pizon
SIMFO Spezielle Immunologie Forschung + Entwicklung GmbH, Bayreuth, Germany

Medical School Hannover, Germany

Prof. Dr. Jonigk and his team work in the field of lung tumor diseases, fibrous lung remodeling under different circumstances, and pulmonary hyper-tension. The focus is on the combination of clinically relevant issues and the morphology of the tissue, and on the expression of DNA, RNA,and proteins in sub-compartments of the lung. With the MMI CellCut Plus laser microdissection system, Prof. Dr. Jongik is able to retrieve high quality samples from the starting material. This significantly improves the accuracy of his results.

“We appreciate the resistant MMI product quality, the professional consulting, and the competent and quick service. MMI instruments are an important basis for our in-situ analysis in cellular tissue. Laser microdissection followed by gene expression analysis is complementary for further routine methods like conventional optical microscopy (fluorescence), in-situ hybridization, and immunohistochemistry.”

Prof. Dr. med. Danny D. Jonigk
Pathological Institute
Medical School Hannover, Germany

Imec Belgium

Chengxun Liu, senior researcher from Imec, Belgium, focuses on the study of physiological property of circulating tumor cells (CTCs). His team aims to identify CTCs from human peripheral blood by their characteristic electrical and physical properties to facilitate the capture of viable CTCs for downstream genotyping. An upright MMI optical tweezer allows CTC mani-pulations directly in their no transparent microfluidic chip.

“The MMI CellManipulator Plus optical tweezer was customized on an upright microscope upon our request. The tweezer has been working reliably, with excellent manipulation power and flexibility on various devices, from simply glass slides to microelectrodes on silicon. The MMI service was also professional, fast and considerate.”

Chengxun Liu, Ph.D.
Bio-Nano Electronics Department
Imec Belgium

Shanghai Institutes for Biological Sciences, China

“I have compared all current available LMD platforms thoroughly and I got to say the CellCut plus is the most impressive one and I highly recommend it to our colleagues. Thanks for bring it to me.”

Dr. Guangdun Peng
Shanghai Institutes for Biological Sciences, China
Molecular Machines & Industries Germany | Switzerland | Hong Kong | USA

Microscopic Single Cell Isolation: Laser Microdissection - Capillary cell sorting - Optical Tweezers  
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