Welcome to the 4th annual European Biomarkers Summit. This year's event will take place in Barcelona, Spain, the dynamic capital city of Catalonia.
MMI - Free Scientific Breakfast Workshop – 6. November 2009, 8:15h
Combining the precision of LaserMicrodissection with the sensitivity of
Nano-immunoassays and Two-dimensional Gel Electrophoresis in
Biomarker Discovery
A conjoint Workshop held by:
Molecular Machines & Industries AG Zurich, Switzerland and
Cell Biosciences, Inc., Santa Clara, CA, USA
Introduction & Moderation: Dr. Antje Plaschke-Schlütter MMI AG Zurich, Business Development and Scientific Marketing
Dr. Plaschke-Schluetter received a doctorate in Cell & Molecular Biology being a graduate student of Prof. W. Birchmeier at MDC Berlin and holds a business degree from GSBA Zurich.
Caroline Stevens, Marketing Assistant Molecular Machines & Industries AG
Presenter 1: Tadashi Kondo, MD, PhD, Proteome Bioinformatics Project, National Cancer Center Tokyo, Japan
Dr. Tadashi Kondo holds an MD and a Phd degree and leads the Proteome Bioinformatics Project. He received several awards for his pioneering work.
Presenter 2: David Voehringer, PhD, Director Applications, Cell Biosciences Inc., Santa Clara, CA, USA
Dr. Voehringer received his postdoctoral training as an NIH fellow under the supervision of Leonard Herzenberg, Department of Genetics, Stanford Medical School he holds a PhD in Cancer Biology from M.D. Anderson Cancer Center.
Laser microdissection is a technology used to isolate specific cell populations from a heterogeneous tissue section under microscopic observation by means of a highly focused laser beam. A high number of publications in a broad range of medical and scientific journals show its increasing importance and usage; however, the main fields of application are within biomedical research. Molecular profiling and biomarker discovery is the focus in cancer research, studies of neurology related diseases, immunology caused diseases, in dermatology as well as in cardiology. The microscopic visualization of the cells permits the specific selection of affected versus non-affected cells, of normal, premalignant and malignant cells. Laser Microdissection on surgically resected patient tissue combined with Proteomics will be presented by Dr. Tadashi Kondo. He developed a high through-put protocol based on high sensitive fluorescent dye usage, a large format 2D gel apparatus for two-dimensional difference gel electrophoresis (2D-DIGE), high through-put western blotting, data-mining methods, and a proteome database.
The Cell Biosciences CB1000 system introduced by Dr. Voehringer enables the measurement of cell signaling phospho-proteins and discovery of novel biomarkers in extremely small primary biological samples, such as rare cell populations, fine-needle aspirates, stem cells, and laser microdissections. This workshop will present fundamentals of the CB1000‘s assay technology and examples of data from various cells types, with emphasis on recent results using cells from microdissected tumor tissue sections.
To register for the mmi Workshop: click here
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