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Reduced sensitivity to reward is common in stress-related neuropsychiatric disorders, including symptoms such as anhedonia and apathy in depression and schizophrenia, for example. Animal models are essential to increase understanding of the underlying neurobiology. Explore in this webinar how chronic stress affects reward processing in mice and learn more about the underlying neural mechanisms.
In this webinar, you will learn:
- Stress effects on reward behavior and BA-NAc neural pathway activity in mice
- Replicating stress effects on reward by manipulating the activity of BA-NAc neurons
- The importance of laser capture microdissection to study specific neuronal populations
- RNA-sequencing with LCM-collected neurons
Join this expert webinar to hear Professor Christopher Pryce, Professor of Neurobiology and Biological Psychiatry at the University of Zurich, discuss the effects of chronic stress on reward behavior and associated activity in the glutamate neuron pathway. Additionally, learn the importance of molecular tools, in particular laser capture microdissection for the identification and collection of BA-NAc neuron populations for RNA-sequencing.
Discover more about the MMI microdissection solution