Laser Microdissection for highest sample integrity: MMI CellCut
The MMI CellCut facilitates precise and contamination-free dissection of cell clusters, single cells or subcellular compartments from various types of tissues including fresh frozen, paraffin-embedded and archived slides, cytospins, smears and even living cells.

Have a look how it works
In the following video you will see how to select cells of interest, how to cut them and how you verify the successful collection

“I have compared all current available LMD platforms thoroughly and I got to say the CellCut plus is the most impressive one and I highly recommend it to our colleagues. Thanks for bring it to me.”
Chinese Academy of Sciences
Guangzhou, China
“We appreciate the resistant MMI product quality, the professional consulting, and the competent and quick service. MMI instruments are an important basis for our in-situ analysis in cellular tissue. The MMI CellCut laser microdissection followed by gene expression analysis is complementary for further routine methods like conventional optical microscopy (fluorescence), in-situ hybridization, and immunohistochemistry.”
Hannover Medical School
Hanover, Germany
The MMI CellCut provides a fully auditable and automatically documented workflow:
1. Prepare your sample
The section is placed on the MMI MembraneSlide, a frame slide covered with a thin membrane that is inert and has negligible autofluorescence. Afterwards, the MMI MembraneSlide is inverted and placed onto a glass slide for protection against contamination. Now the sample is sandwiched between the membrane and the glass.
2. Select your cells – any size and flexible shapes
The cells of interest can be selected quickly and easily using the MMI CellTools software. The touch screen enables straightforward selection of one or multiple spots, either using the interactive pen or using the mouse, by freehand or with predefined geometrical shapes. The stage is moving to trace the path drawn while the laser is fixed and focused from below.
3. Excise your cells – automatically and with sub-micron precision
The thin laser cutting path enables a precise and gentle extraction of the selected cell at an outstanding speed.
4. Collect your cells – full visual sample inspection after cutting
The isolated target cell is collected by lowering and lifting of the adhesive MMI IsolationCap held from above. The sample morphology remains 100% intact. After cutting, the sample can be visually inspected on the cap. Just add some buffer and invert the tube to suspend your cells for downstream processing.